Should we use Aspirin with Warfarin?

Use and Associated Risks of Concomitant Aspirin Therapy With Oral Anticoagulation in Patients With Atrial Fibrillation
Circulation 2013;128(7):721-728.

Should we use Apsirin with Warfarin?

Probably not, as there is a significantly increased risk of bleeding (aHR = 1.5; 95% CI 1.2 – 2.0), and little to no difference in cardiovascular events, even in those with a Hx of AMI or CVA who were therefore receiving aspirin as ‘secondary’ prevention.

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