TL
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TL wrote a new post, Evidence Based Medicine – an Oral History 10 years, 9 months ago
Andrew Knight writes:This fascinating video looks at the origins and future of the evidence based medicine movement through interviews with the major players – Guyatt, Sackett, Haynes and more.
Even they […]
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TL wrote a new post, Should we stent renal artery stenosis? 10 years, 9 months ago
Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis — NEJM
Patients with more than 60% renal artery stenosis and hypertension were randomised to receive stunting plus medical treatment or […]
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TL wrote a new post, Nuts to you – in the nicest possible way 10 years, 9 months ago
Association of Nut Consumption with Total and Cause-Specific Mortality — NEJMIn a study of health professionals, nut consumption was associated with reduced all-cause mortality.
This was primarily due to a […]
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TL wrote a new post, Warfarin Interactions With Antibiotics 10 years, 9 months ago
Warfarin Interactions With Antibiotics in the Ambulatory Care Setting [JAMA Intern Med. 2014]
A retrospective, longitudinal cohort study evaluated patients receiving warfarin between January 1, 2005, and March […]
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TL wrote a new post, New Lipid Guidelines – Hooray! 11 years ago
This week, the American College of Cardiology and American Heart Association (ACC/AHA) released new guidelines for the management of Lipids.
The new guidelines are a major shift in thinking. They are far closer […]
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TL replied to the topic Should I take a cholesterol tablet? If so, which one? in the forum Cardiovascular disease 11 years ago
This week, the American College of Cardiology and American Heart Association (ACC/AHA) released new guidelines for the management of Lipids.
The new guidelines are a major shift in thinking. They are far closer to the proposed POQ in the discussion above than to the previous guidelines. Spooky. This is clearly cause and effect. Who would have…[Read more]
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TL wrote a new post, Top 20 POEMS for 2012 11 years, 1 month ago
Mark Ebell is the editor of Essential Evidence Plus, a great source of POEMS, and to which I subscribe.
He has nominated the top POEMS of 2012. The list was published in The American Family Physician last […]
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TL replied to the topic Should I take a cholesterol tablet? If so, which one? in the forum Cardiovascular disease 11 years, 1 month ago
Thanks Dan,
The studies quoted by Ben confirm that the benefits of statins are unrelated to the baseline LDL level, but they do have some benefit in primary prevention. The extent of that benefit is dependent on absolute cardiac risk.
Measuring lipids once to determine absolute cardiac risk (at age 35-55) seems like a valid…[Read more]
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TL wrote a new post, No pain no gain – Exercise is good for pain in hip and knee osteoarthritis 11 years, 1 month ago
Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis
Paul S. Mueller, MD, MPH, FACP Reviewing Uthman OA et al., BMJ 2013 Sep 20; […] -
TL replied to the topic CVD Risk Calculations in the forum Clinical Questions 11 years, 1 month ago
James McCormack (of http://therapeuticseducation.org, my favourite podcast) has a Risk Calculator at
http://bestsciencemedicine.com/chd/calc2.html
This shows the effect of different treatments on risk, and displays the risk pictorially. Even though it is in beta, it is worth a look.The algorithm used in this tool (and the Australian [Read more]
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TL wrote a new post, Effect of vitamin D supplemention on depression – none 11 years, 1 month ago
Effect of vitamin D supplement on depression scores in people with low levels of serum 25-hydroxyvitamin D: nested case-control study and randomised clinical trial Kjærgaard M, Waterloo K, Wang CE, Almås B, […] -
TL wrote a new post, Vitamin D – No benefit on bone density or fractures 11 years, 1 month ago
Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis
A team of our colleagues from New Zealand have performed a meta analysis of the effects of Vit D supplementation on […] -
TL wrote a new post, NNT – Delusions of Benefit in the International Stroke Trial 11 years, 1 month ago
NNT – Delusions of Benefit in the International Stroke TrialThe team at NNT (Number Needed to Treat) have looked at the International Stroke Trial 3 – the definitive trial on whether thrombolytics are useful in […]
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TL wrote a new post, Fibrates: Statin’s Trusty Sidekick or Lackluster Fallback? 11 years, 1 month ago
Fibrates: Statin’s Trusty Sidekick or Lackluster Fallback?
This weeks Tools for Practice examines the evidence for Fibrates.Clinical Question: Do fibrates reduce cardiovascular (CV) events?
Bottom-line
When […] -
TL wrote a new post, Injections for CTS 11 years, 1 month ago
Steroid injections for carpal tunnel syndrome provide significant short term […]
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TL wrote a new post, Does This Patient With Shoulder Pain Have Rotator Cuff Disease? 11 years, 1 month ago
A recent article in JAMA looked at the accuracy of clinical assessment of the shoulder in assessing the presence of rotator cuff disease.Most helpfully, the article was accompanied by this cool video […]
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TL started the topic Should I take a cholesterol tablet? If so, which one? in the forum Cardiovascular disease 11 years, 1 month ago
Here’s a discussion for comment. When a consensus is reached, more evidence is added, and the language is improved, this may become a POQ.
There is no evidence that taking medications to lower your cholesterol per se is worthwhile.
However, there is good evidence through many studies that statins can be beneficial in the secondary prevention…[Read more]
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admin posted an update 11 years, 1 month ago
Building the social part of the site with buddy press
