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  • Profile picture of TL

    TL wrote a new post, Should we use Aspirin with Warfarin? 11 years, 4 months ago

    Use and Associated Risks of Concomitant Aspirin Therapy With Oral Anticoagulation in Patients With Atrial Fibrillation
    Circulation 2013;128(7):721-728.

    Should we use Apsirin with Warfarin?

    Probably not, as […]

  • Profile picture of TL

    TL wrote a new post, Evidence Based Medicine – an Oral History 11 years, 4 months ago

    ThumbnailAndrew Knight writes:

    This fascinating video looks at the origins and future of the evidence based medicine movement through interviews with the major players – Guyatt, Sackett, Haynes and more.

    Even they […]

  • Profile picture of TL

    TL wrote a new post, Should we stent renal artery stenosis? 11 years, 4 months ago

    Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis — NEJM

    Patients with more than 60% renal artery stenosis and hypertension were randomised to receive stunting plus medical treatment or […]

  • Profile picture of TL

    TL wrote a new post, Nuts to you – in the nicest possible way 11 years, 4 months ago

    ThumbnailAssociation of Nut Consumption with Total and Cause-Specific Mortality — NEJM

    In a study of health professionals, nut consumption was associated with reduced all-cause mortality.

    This was primarily due to a […]

  • Profile picture of TL

    TL wrote a new post, Warfarin Interactions With Antibiotics 11 years, 4 months ago

    Warfarin Interactions With Antibiotics in the Ambulatory Care Setting [JAMA Intern Med. 2014]

    A retrospective, longitudinal cohort study evaluated patients receiving warfarin between January 1, 2005, and March […]

  • Profile picture of Vanessa Fernandez

    Vanessa Fernandez became a registered member 11 years, 6 months ago

  • Profile picture of Chris Freeman

    Chris Freeman became a registered member 11 years, 6 months ago

  • Profile picture of Jenny May

    Jenny May became a registered member 11 years, 6 months ago

  • Profile picture of TL

    TL wrote a new post, New Lipid Guidelines – Hooray! 11 years, 6 months ago

    This week, the American College of Cardiology and American Heart Association (ACC/AHA) released new guidelines for the management of Lipids.

    The new guidelines are a major shift in thinking. They are far closer […]

  • Profile picture of TL

    TL replied to the topic Should I take a cholesterol tablet? If so, which one? in the forum Cardiovascular disease 11 years, 6 months ago

    This week, the American College of Cardiology and American Heart Association (ACC/AHA) released new guidelines for the management of Lipids.

    The new guidelines are a major shift in thinking. They are far closer to the proposed POQ in the discussion above than to the previous guidelines. Spooky. This is clearly cause and effect. Who would have…[Read more]

  • Profile picture of Paresh Dawda

    Paresh Dawda became a registered member 11 years, 7 months ago

  • Profile picture of ralph audehm

    ralph audehm became a registered member 11 years, 7 months ago

  • Profile picture of TL

    TL wrote a new post, ACE Inhibitors best for hypertension in diabetes 11 years, 7 months ago

    Comparative effectiveness of renin-angiotensin system blockers and other antihypertensive drugs in patients with diabetes: systematic review and bayesian network meta-analysis | BMJ
    Hon-Yen Wu et al
    BMJ […]

  • Profile picture of Charlotte Hespe

    Charlotte Hespe became a registered member 11 years, 7 months ago

  • Profile picture of Walter Kmet

    Walter Kmet became a registered member 11 years, 7 months ago

  • Profile picture of TL

    TL wrote a new post, Top 20 POEMS for 2012 11 years, 7 months ago

    Mark Ebell is the editor of Essential Evidence Plus, a great source of POEMS, and to which I subscribe.

    He has nominated the top POEMS of 2012. The list was published in The American Family Physician last […]

  • Profile picture of TL

    TL replied to the topic Should I take a cholesterol tablet? If so, which one? in the forum Cardiovascular disease 11 years, 7 months ago

    Thanks Dan,

    The studies quoted by Ben confirm that the benefits of statins are unrelated to the baseline LDL level, but they do have some benefit in primary prevention. The extent of that benefit is dependent on absolute cardiac risk.

    Measuring lipids once to determine absolute cardiac risk (at age 35-55) seems like a valid…[Read more]

  • Profile picture of TL

    TL wrote a new post, No pain no gain – Exercise is good for pain in hip and knee osteoarthritis 11 years, 7 months ago

    Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis
    Paul S. Mueller, MD, MPH, FACP Reviewing Uthman OA et al., BMJ 2013 Sep 20; […]

  • Profile picture of TL

    TL replied to the topic CVD Risk Calculations in the forum Clinical Questions 11 years, 7 months ago

    James McCormack (of http://therapeuticseducation.org, my favourite podcast) has a Risk Calculator at
    http://bestsciencemedicine.com/chd/calc2.html
    This shows the effect of different treatments on risk, and displays the risk pictorially. Even though it is in beta, it is worth a look.

    The algorithm used in this tool (and the Australian [Read more]

  • Profile picture of TL

    TL wrote a new post, Effect of vitamin D supplemention on depression – none 11 years, 7 months ago

    ThumbnailEffect of vitamin D supplement on depression scores in people with low levels of serum 25-hydroxyvitamin D: nested case-control study and randomised clinical trial Kjærgaard M, Waterloo K, Wang CE, Almås B, […]

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